SynopsisCodesDifferential Diagnosis & PitfallsBest TestsReferences
Aortoiliac occlusive disease
Other Resources UpToDate PubMed

Aortoiliac occlusive disease

Contributors: Ryan Hoefen MD, PhD
Other Resources UpToDate PubMed


Aortoiliac occlusive disease, also known as Leriche syndrome, is a narrowing or blocking of iliac arteries caused by plaque buildup. It is a very common condition that typically occurs in older adult males, although any adult can be affected. Risk factors include smoking, hypercholesterolemia, hypertension, obesity, family history of heart disease, diabetes mellitus, Takayasu arteritis, or thromboangiitis obliterans. The most characteristic symptom is intermittent lower limb claudication defined by cramping in calf, thigh, hip, or buttock muscles following exercise. Other symptoms include erectile dysfunction, decreased femoral pulse, cold extremities, and/or signs of advancing disease such as ischemic ulcers on lower extremities, muscle weakness, and lower limb paresthesia.

Treatment includes lifestyle changes, endovascular therapy, and medication to decrease clotting risk.


I74.09 – Other arterial embolism and thrombosis of abdominal aorta

233956002 – Aortoiliac atherosclerosis

Differential Diagnosis & Pitfalls

  • Spinal stenosis (see Cervical spinal stenosis, Lumbar spinal stenosis)
  • Osteoarthritis
  • Popliteal entrapment syndrome
  • Complex regional pain syndrome
  • Peripheral neuropathy
  • Venous thrombosis (eg, Deep vein thrombosis)

Best Tests

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Last Updated:10/31/2019
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Aortoiliac occlusive disease
A medical illustration showing key findings of Aortoiliac occlusive disease : Claudication, Erectile dysfunction, Leg cramp, Buttock pain
Copyright © 2024 VisualDx®. All rights reserved.