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Argyria

See also in: External and Internal Eye,Nail and Distal Digit
Contributors: Michael D. Tharp MD, Neil Shear MD
Other Resources UpToDate PubMed

Synopsis

Argyria refers to the deposition of silver or silver-containing compounds within tissue(s). Argyria may occur locally due to direct contact with silver-containing materials, or as a generalized phenomenon when there is systemic dissemination of the silver. The features of argyria become apparent from 6 months to several years following initial exposure to the product containing silver.

Codes

ICD10CM:
L81.8 – Other specified disorders of pigmentation

SNOMEDCT:
255636009 – Argyria

Look For

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated:09/10/2017
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Argyria
See also in: External and Internal Eye,Nail and Distal Digit
A medical illustration showing key findings of Argyria : Diffuse blue nails, Sclera/bulbar conjunctiva color change, Silver compound exposure, Photodistributed
Clinical image of Argyria - imageId=2193996. Click to open in gallery.  caption: 'Blue-gray discoloration of the sclera and periorbital skin after use of a topical silver-containing antiseptic.'
Blue-gray discoloration of the sclera and periorbital skin after use of a topical silver-containing antiseptic.
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