Atrophoderma in Adult
Lesions occur most often on the trunk, most commonly the lumbosacral region of the back. Initially, lesions are localized, then progress to involve other areas over months to years before stabilizing. Unlike morphea, atrophoderma is not thought to have an inflammatory stage and is asymptomatic.
The condition occurs disproportionately in females, usually in the second and third decades. However, it has been reported in infancy and old age.
Whether atrophoderma is a nonsclerotic, atrophic variant of morphea or a distinct entity is debated. The etiology is unknown, although it has been theorized that cells with an aberrant T-cell phenotype may be the cause of collagen fiber destruction. The role of Borrelia burgdorferi in the pathogenesis of this entity is highly controversial.
Linear atrophoderma of Moulin is a related condition that follows the lines of Blaschko. It typically develops in childhood or adolescence.
L90.3 – Atrophoderma of Pasini and Pierini
43398005 – Atrophoderma of Pasini and Pierini
Differential Diagnosis & Pitfalls