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Black salve necrosis
Other Resources UpToDate PubMed

Black salve necrosis

Contributors: Kishan Pandya BS, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Black salve products have been widely advertised as an alternative medicine to treat a variety of dermatologic conditions including skin cancers, furuncles, nevi, and skin tags, among other conditions. The US Food and Drug Administration (FDA) has issued a warning that black salve is a dangerous product that is not approved to treat any of these skin conditions. It contains corrosive ingredients such as zinc chloride and sanguinarine (Sanguinaria canadensis, also known as bloodroot). These ingredients interfere with RNA and DNA gene expression and cell division, which leads to the inhibition of skin proliferation and subsequent necrosis.

Codes

ICD10CM:
T54.94XA – Toxic effect of unspecified corrosive substance, undetermined, initial encounter

SNOMEDCT:
735470000 – Acute skin injury caused by corrosive substance

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

Best Tests

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Management Pearls

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Therapy

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References

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Last Reviewed:08/08/2022
Last Updated:09/11/2022
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Black salve necrosis
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A medical illustration showing key findings of Black salve necrosis
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