Bowenoid papulosis - Anogenital in
BP typically occurs in young sexually active adults. There is an equal male-to-female ratio. Lesions are usually asymptomatic and occur primarily in the genital and perianal region.
BP has a variable course, with a frequent potential for spontaneous regression as well as persistence and recurrence. A postsurgical excision recurrence rate of up to 20.3% has also been documented.
The risk of progression to invasive SCC in immunocompetent patients is estimated at 2.6%. In immunocompromised patients, the risk of invasive malignancy may be higher; one-half of HIV-infected patients with anogenital warts have SCCIS on histology.
D04.9 – Carcinoma in situ of skin, unspecified
402913004 – Bowenoid papulosis
Differential Diagnosis & Pitfalls
- The lesions of BP are often mistaken for condyloma, lichen planus, and psoriasis.
- Unlike Bowen disease and erythroplasia of Queyrat, which are seen in elderly patients, BP is often is seen in younger patients.
- In contrast to BP, the lesions of seborrheic keratosis occur in elderly patients and are rarely seen on the glans.
- Lichen nitidus
- Molluscum contagiosum
- Fordyce spots
- Lichen simplex chronicus
- Squamous cell carcinoma
- Basal cell carcinoma
- Angiokeratoma of scrotum
- Condyloma lata
- Granular cell tumor
- Darier disease
- Hailey-Hailey disease
- Papular acantholytic dermatosis