Bronze baby syndrome
The exact cause of the gray-brown discoloration in bronze baby syndrome is uncertain. Products may accumulate as a result of poor excretion secondary to liver dysfunction.
The discoloration presents after exposure to phototherapy and fades after phototherapy is discontinued. Many affected infants have no sequelae. Others develop kernicterus. Fatalities have been reported.
P83.88 – Other specified conditions of integument specific to newborn
206553008 – Bronze baby
Differential Diagnosis & Pitfalls
- Carbon baby syndrome – Also known as universal acquired melanosis; refers to diffuse hyperpigmentation caused by increased melanin in the epidermis and melanophages in the papillary dermis.
- Cyanosis – Blue discoloration that can be secondary to cardiac abnormalities, pulmonary abnormalities, polycythemia, methemoglobinemia, or hypothermia.
- Gray baby syndrome – Seen in neonates exposed to chloramphenicol. Often fatal from associated shock.
- Jaundice – Yellow or yellow-brown discoloration.