Rare, nonprogressive disorder characterized by multiple joint contractures present at birth. Any joint can be affected, most commonly the knees, toes, hips, shoulders, elbows, wrists, and fingers. It can be caused by any condition that leads to decreased fetal movement in utero. Patients experience limited range of motion or no motion of affected joints. Muscle surrounding affected joints may be hypoplastic. Other findings include hypertelorism, micrognathia, facial dysmorphology, cleft palate, and developmental delay.
Initial treatment is physical therapy to improve joint function and prevent complications.