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Corneoconjunctival intraepithelial neoplasia - External and Internal Eye
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Corneoconjunctival intraepithelial neoplasia - External and Internal Eye

Contributors: Brandon D. Ayres MD, Christopher Rapuano MD, Harvey A. Brown MD, Sunir J. Garg MD, Lauren Patty Daskivich MD, MSHS
Other Resources UpToDate PubMed

Synopsis

Corneal intraepithelial neoplasia (CIN) is a premalignant lesion of the corneal epithelium and limbus. In this condition, the severity of the dysplastic cells is determined by pathology and classified as mild, moderate, or severe. Severe dysplasia has dysplastic cells spanning the epithelial layer but not yet invading the basement membrane and is called carcinoma in situ. The etiology of the dysplastic cellular growth is thought to be actinic damage. The changes from CIN do not cause pain but will reduce vision once the changes invade the visual axis. CIN tends to affect older patients with sun exposure. Patients with CIN may complain of reduced vision, and vision must be checked.

Codes

ICD10CM:
D09.20 – Carcinoma in situ of unspecified eye

SNOMEDCT:
418134006 – Conjunctival intraepithelial neoplasia

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Differential Diagnosis & Pitfalls

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Therapy

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References

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Last Updated:01/19/2015
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Corneoconjunctival intraepithelial neoplasia - External and Internal Eye
A medical illustration showing key findings of Corneoconjunctival intraepithelial neoplasia : Blurred vision, Bulbar conjunctival plaque, Corneal focal white infiltrate, History of severe sunburns
Clinical image of Corneoconjunctival intraepithelial neoplasia - imageId=2915964. Click to open in gallery.
Copyright © 2022 VisualDx®. All rights reserved.