Cutaneous collagenous vasculopathy (CCV) is a very rare superficial cutaneous microangiopathy of unknown etiology. The disease may have a slight preponderance for females and typically affects middle-aged individuals, although one pediatric case has been reported. Fewer than 50 cases have been documented since it was first described in 2000, but it is probably underdiagnosed, since most clinicians do not routinely perform biopsies of acquired telangiectasias.

Individuals present with diffuse telangiectasias, initially on the lower extremities, that progressively spread to the trunk and upper extremities. Lesions typically spare the head and neck, but involvement of these areas has been observed. Telangiectasias are usually asymptomatic, but associated pruritus or pain has been reported. They also characteristically spare the mucosa and nails, but a 2018 case documented recurrent bleeding from gastric mucosal telangiectasias requiring multiple transfusions.