Some medications (eg, checkpoint inhibitors) can trigger development of a colitis similar to inflammatory bowel disease that may warrant treatment with immune suppressant therapy. In this instance, diarrhea will persist beyond the cessation of the offending agent, and further workup with colonoscopy will likely reveal the diagnosis.
Other medications injure the lining of the bowel causing mucositis, such as chemotherapy, and hence cause diarrhea.
K52.1 – Toxic gastroenteritis and colitis
62315008 – Diarrhea
Differential Diagnosis & Pitfalls
Drug Reaction Data