Risk factors for hypoglycemia in adults include inadequate patient education, changes in caloric intake (enteral or parenteral), improper timing of insulin with meals, decreased renal or hepatic clearance, tapering of steroids, acute illness dementia, and advanced age (older than 65 years).
In neonates, hypoglycemia may be related to endocrine deficiencies; low birth size; delayed first feeding; severe renal, liver, or heart disease; sepsis; or hereditary fructose intolerance.
Signs and symptoms depend on the causes but may be adrenergic (including agitation, tremor, hunger, weakness, palpitation, nausea, irritability, sweating, and tachycardia) or neuroglycopenic (including confusion, lethargy, paresthesia, blurred vision, headache, dizziness, behavioral changes, seizures, loss of consciousness, and coma). An infant may present with irritability, poor feeding, tachypnea, cyanosis, hypothermia, or lethargy within a few hours after birth.
E16.2 – Hypoglycemia, unspecified
302866003 – Hypoglycemia
Differential Diagnosis & Pitfalls
Similar autonomic symptoms without hypoglycemia have a broad differential:
Drug Reaction Data