Intertrigo in Infant/Neonate
L30.4 – Erythema intertrigo
58759008 – Intertrigo
Differential Diagnosis & Pitfalls
- Perianal streptococcal infection as well as streptococcal infection of the neck, axillae, or inguinal folds manifests with intense, well-circumscribed erythema with moist erosions. A bacterial cause should be suspected if standard topical treatment is ineffective.
- Seborrheic dermatitis is usually seen in the scalp and forehead of infants, but it can be seen in skin folds and the diaper area.
- Candidiasis often involves the diaper area and involves the skin folds (whereas an irritant dermatitis will spare the skin folds). Look for satellite papules and/or pustules.
- Langerhans cell histiocytosis – If involvement is widespread, includes petechiae / purpura, has associated hepatosplenomegaly, and/or standard treatments are not effective.
- Hyperimmunoglobulinemia E syndrome
- Granular parakeratosis has been reported in the diaper area.
- Acrodermatitis enteropathica