- Conjunctival injection without exudate
- Red lesions of the mouth or pharynx
- Acute hand and foot edema followed by peeling
- Polymorphous cutaneous eruption
- Lymphadenopathy (usually cervical)
The most significant and potentially life-threatening complications are cardiovascular. Pericarditis, myocarditis, coronary arteritis, and endocarditis leading to arrhythmias can occur as early as 7 days from the onset of fever.
A multisystem inflammatory syndrome potentially linked to COVID-19 has been reported in children and young adults; clinical features include Kawasaki-like and toxic shock syndrome-like presentations.
Childhood sexual abuse is a problem of epidemic proportions affecting children of all ages and economic and cultural backgrounds. A variety of dermatologic conditions causing erythema of the perineum, including KD, should be considered when sexual abuse is suspected. Although awareness is increasing, it is often challenging to differentiate findings attributable to child abuse from those of other benign anogenital skin conditions.