Lobular capillary hemangiomas, also known as pyogenic granulomas (PGs), are rapidly growing, benign vascular growths of undetermined etiology. The term "pyogenic granuloma" is a misnomer, as the lesion(s) are neither granulomatous nor infectious. PGs usually present as a solitary red papule or nodule that ulcerates and bleeds easily.

Trauma and the production of angiogenic growth factors are some of the postulated causal factors. PGs may also arise during pregnancy (the so-called "pregnancy tumor") or in the course of treatment with certain medications (protease inhibitors, retinoids, some chemotherapeutic drugs). They are more common in children and individuals of childbearing potential. Treatment by removing the lesion is indicated in cases of bleeding, emotional distress, discomfort, or when the diagnosis is in doubt.

PG of the eye area has been reported after oculoplastic and strabismus procedures following incisions of the conjunctiva. In addition, PG has occurred after placement of punctal plugs and in association with Actinomyces canaliculitis.