Mastocytoma in Infant/Neonate
Mastocytomas account for 10%-15% of pediatric cutaneous mastocytosis. Mastocytomas present with one or a few (up to 3) papules The lesions may be pruritic and may swell spontaneously or after thermal, mechanical, or chemical stimulation. Thermal stimulation can occur after a bath, emotional stress, physical exertion, or with change in seasons. Mechanical stimulation can occur during surgery or following administration of vaccines. Chemical stimulation may be with foods or with topical or oral medication.
Mild systemic signs and symptoms may include flushing, bone pain, and headache. Hypotension / anaphylaxis, esophageal irritation, intestinal bleeding, and lymphadenopathy are less common with solitary mastocytomas but more frequently accompany other forms of cutaneous mastocytosis, such as urticaria pigmentosa and diffuse cutaneous mastocytosis.
D47.01 – Cutaneous mastocytosis
404171008 – Mastocytoma
Differential Diagnosis & Pitfalls