Mayaro virus infection
Patients present with fever, a nonspecific rash, arthralgias, and eye pain. The rash is typically seen around day 5 of the illness. Other symptoms that may be present include headache, retro-orbital pain, nausea, vomiting, diarrhea, and photophobia. Symptoms typically resolve over about 5 days, but arthralgias can persist for weeks to months and up to 1 year after acute illness.
The symptoms of Mayaro virus are similar to those seen following infection with other alphaviruses including chikungunya virus, and it may be impossible to distinguish these infections based solely on the clinical history and physical examination.
A92.8 – Other specified mosquito-borne viral fevers
9164007 – Mayaro fever
- Other alphaviruses including chikungunya virus – Serology or PCR can be checked.
- Malaria – Malaria antigen and blood smear should be obtained.
- Dengue fever – Polyarthralgia is less common with Dengue fever. Serology can be checked.
- Zika virus – Check serology and PCR.
- Yellow fever – Should be considered in travelers to endemic regions of South America. Patients may have jaundice. Diagnosis is with serology or PCR.
- Typhoid fever – Patients typically have fever and "rose spots." Diagnosis is typically made by culture of the blood or stool.
- Measles – The rash typically begins on the face before spreading to the trunk and extremities. Diagnosis is by serology or PCR.