Common condition occurring in response to a physical or perceived motion, usually in the context of travel / transportation. Characterized by gastrointestinal, central nervous system, and autonomic symptoms.

Although motion sickness can occur in nearly any individual, some individuals may be more susceptible. Patients at increased risk include females (especially those who are pregnant or using oral contraceptives), children younger than 2 years, migraine sufferers, and individuals with other sensory illnesses.

Clinical symptoms include belching, diaphoresis, dizziness, increased salivation, malaise, nausea, vomiting, and warmth. Physical signs are usually absent, although pallor may sometimes occur.

Motion sickness will usually improve or resolve with continuous / repeated exposure to the inciting stimulus. Antihistamines, anticholinergics, antidopaminergics, benzodiazepines, antiemetics, and GABA agonists can be used to prevent, manage, or treat motion sickness.