Multiple endocrine neoplasia type 2A
Patients are at risk of developing tumors in the thyroid, parathyroid, and adrenal glands as well as nerve defects such as neuromas. MEN2A is characterized by medullary thyroid carcinomas, primary hyperparathyroidism, and pheochromocytomas.
MEN2A often manifests before the fourth decade of life (most often between the ages of 5 and 25 years). Diarrhea and medullary thyroid carcinoma are usually the initial presenting symptoms. Other findings include cervical lymphadenopathy, depressed mood, constipation, fatigue, headache, flushing, hypertension, memory impairment, pruritus, and palpitations.
Related topics: MEN1, MEN2B
E31.22 – Multiple endocrine neoplasia [MEN] type IIA
721188000 – Multiple endocrine neoplasia type 2A
Differential Diagnosis & Pitfalls