Nodular hidradenoma is more common in females and can occur in any ethnicity and at any age including infancy, although it is most common in the fourth decade of life. There are currently no known risk factors. Local recurrence can also occur, especially with inadequate surgical excision.
Hidradenocarcinoma (also known as malignant nodular hidradenoma [MNH]) is a very rare malignant tumor that can arise from nodular hidradenoma, although it typically arises de novo.
D23.9 – Other benign neoplasm of skin, unspecified
253020008 – Hidradenoma of skin
Differential Diagnosis & Pitfalls
- Basal cell carcinoma
- Squamous cell carcinoma
- Hidradenocarcinoma – Typically larger than nodular hidradenomas and asymmetric in configuration. Hidradenocarcinomas usually are seen in the sixth to seventh decade of life. They grow slowly and may or may not be ulcerated.
- Eccrine poroma
- Metastatic renal cell carcinoma
- Glomus tumor