Approximately 40% of cases of pancreatic pseudocyst resolve without intervention, but they may produce a wide range of signs, symptoms, and clinical manifestations. These may include abdominal mass, abdominal pain, fever, chills, and jaundice.
Complications may include duodenal obstruction or biliary obstruction due to pseudocyst expansion, fistula formation into adjacent viscera including the peritoneal, pericardial, and pleural cavities, spontaneous pseudocyst infection, and pseudoaneurysm.
K86.3 – Pseudocyst of pancreas
111374002 – Pseudocyst of pancreas
Differential Diagnosis & Pitfalls
- Acute pancreatitis complication
- Walled-off pancreatic necrosis – Imaging will demonstrate heterogenous fluid collection with both liquid and nonliquid components (as opposed to homogenous density and only liquid components seen on imaging for pancreatic pseudocyst).
- Pancreatic retention cysts
- Pancreatic mucinous nonneoplastic cysts
- Pancreatic lymphoepithelial cysts
- Benign pancreatic cysts
- Pancreatic cystic tumors / carcinoma