An uncommon condition due to abrupt-onset infarction or hemorrhage into the pituitary gland, typically associated with a pituitary adenoma, and characterized by severe headache and visual disturbance. Endocrine abnormalities of hypopituitarism can contribute to life-threatening hypotension. Other common signs and symptoms include vomiting, ophthalmoplegia, diplopia, visual field defect, vision loss, and altered mental state.
Management includes surgical resection and hormone replacement therapy. Best outcomes are when diagnosis and treatment occurs within a few days to a week. Delayed treatment decreases chances to improve visual deficit.
Potentially life-threatening emergency
Pituitary apoplexy
Alerts and Notices
Synopsis

Codes
ICD10CM:
E23.6 – Other disorders of pituitary gland
SNOMEDCT:
237701005 – Pituitary apoplexy
E23.6 – Other disorders of pituitary gland
SNOMEDCT:
237701005 – Pituitary apoplexy
Best Tests
Subscription Required
Drug Reaction Data
Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.
Subscription Required
References
Subscription Required
Last Updated:01/10/2023