SynopsisCodesLook ForDiagnostic PearlsDifferential Diagnosis & PitfallsBest TestsManagement PearlsTherapyDrug Reaction DataReferences

Information for Patients

View all Images (21)

Psoriasis - Anogenital in
See also in: Overview,Hair and Scalp,Nail and Distal Digit
Other Resources UpToDate PubMed

Psoriasis - Anogenital in

See also in: Overview,Hair and Scalp,Nail and Distal Digit
Contributors: Jeffrey M. Cohen MD, Sophia Delano MD, Amy Swerdlin MD, Belinda Tan MD, PhD, Susan Burgin MD
Other Resources UpToDate PubMed


Psoriasis is a chronic inflammatory disease of the skin with a likely immunologic basis. Hyperproliferation of epidermal cells results in thickened, scaly skin. Psoriasis is commonly categorized as mild (covers less than 3% of the body), moderate (3%-10%), or severe (over 10%). Psoriasis is fairly common in childhood but rare in infancy. (See infantile psoriasis.)

There are many differing clinical patterns of psoriasis, including plaque type, guttate psoriasis (which often follows strep throat), palmar-plantar psoriasis, erythrodermic psoriasis, and pustular psoriasis. Involvement of the inguinal areas and axillae is termed inverse psoriasis. Psoriasis can often be seen in the diaper area and in the skin folds of very young children.

Anogenital psoriasis is rather common and usually is comparable to psoriasis found elsewhere on the body. It can be isolated to the genitalia but is often part of a more generalized affliction. In females, inverse psoriasis is found on the mons pubis, labia majora, perirectal skin, and inguinal folds.


L40.0 – Psoriasis vulgaris

9014002 – Psoriasis

Look For

Subscription Required

Diagnostic Pearls

Subscription Required

Differential Diagnosis & Pitfalls

  • Tinea cruris can be easily differentiated from psoriasis by the demonstration of hyphal elements on potassium hydroxide (KOH) preparation. Concurrent Tinea pedis would also favor tinea cruris over psoriasis.
  • Diaper irritant contact dermatitis will present as red, inflamed plaques sparing the innermost folds of the intertriginous areas that are relatively shielded from irritants.
  • Allergic contact dermatitis has clusters of often pruritic vesicles in a geometric pattern outlining the exposed area.
  • Lichen planus presents with pruritic violaceous papules with overlying white reticulated markings (Wickham striae), most often involving the wrists and ankles.
  • Seborrheic dermatitis is yellowish and greasier, as opposed to the silvery, dry scale of psoriasis. Lesions are also ill-defined, unlike the well-defined plaques of psoriasis.
  • Candidiasis displays brightly erythematous plaques like anogenital psoriasis but will likely also have adjacent, smaller satellite lesions.
  • Lichen sclerosus presents as hypopigmented, slightly atrophic plaques with occasional fissures, petechial and labial fusion, and reabsorption.
  • Cutaneous Crohn disease may present as erythema, firm papules, or labial swelling that is usually not as well demarcated as psoriasis and should be considered in the diagnosis in any patient with a history of inflammatory bowel disease. Fistulas and perianal skin tags may also be seen in cutaneous Crohn disease.
  • Fixed drug eruption

Best Tests

Subscription Required

Management Pearls

Subscription Required


Subscription Required

Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

Subscription Required


Subscription Required

Last Reviewed:08/06/2022
Last Updated:07/09/2023
Copyright © 2024 VisualDx®. All rights reserved.
Patient Information for Psoriasis - Anogenital in
Print E-Mail Images (21)
Contributors: Medical staff writer
Premium Feature
VisualDx Patient Handouts
Available in the Elite package
  • Improve treatment compliance
  • Reduce after-hours questions
  • Increase patient engagement and satisfaction
  • Written in clear, easy-to-understand language. No confusing jargon.
  • Available in English and Spanish
  • Print out or email directly to your patient
Copyright © 2024 VisualDx®. All rights reserved.
Psoriasis - Anogenital in
See also in: Overview,Hair and Scalp,Nail and Distal Digit
A medical illustration showing key findings of Psoriasis : Erythroderma, Extensor distribution, Nail pits, Scalp, Subungual hyperkeratosis, Onycholysis
Clinical image of Psoriasis - imageId=329024. Click to open in gallery.  caption: 'Well-demarcated annular scaly papules and plaques with erythema on the back.'
Well-demarcated annular scaly papules and plaques with erythema on the back.
Copyright © 2024 VisualDx®. All rights reserved.