Reticulate acropigmentation of Kitamura
RAPK was first described in the Japanese population, and it has since been documented in many ethnic groups around the world. RAPK is seen more commonly in females than in males.
RAPK is caused by a mutation in the ADAM10 gene on chromosome 15q21.
L81.8 – Other specified disorders of pigmentation
239133004 – Reticulate acropigmentation of Kitamura
Differential Diagnosis & Pitfalls
- – Hyperpigmented and hypopigmented macules; predominantly males will be affected.
- (DUH) – Hyperpigmented and hypopigmented macules diffusely present over trunk; autosomal dominant.
- Familial progressive hyperpigmentation – This will be present at birth or soon after. Hyperpigmented patches of varying sizes occur on skin and mucous membranes.
- Cole syndrome