Sebaceous hyperplasia in newborn
Alerts and Notices
Synopsis

Sebaceous hyperplasia occurs in nearly half of term newborns with premature infants being less commonly affected.
Codes
ICD10CM:L73.8 – Other specified follicular disorders
SNOMEDCT:
403852003 – Neonatal sebaceous gland hyperplasia
Look For
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Diagnostic Pearls
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Differential Diagnosis & Pitfalls
- Milia – The papules of milia are typically discrete, solitary, and whiter in color compared to sebaceous hyperplasia.
- Acne neonatorum – Follicular-based papules that may have patulous ostia (open comedones) or smooth papules (closed comedones).
- Nevus sebaceus – Agminated yellow, waxy papules, also composed of sebocytes, may occur on the face. These usually coalesce into a plaque.
- Micronodular juvenile xanthogranulomas – Multiple yellow or red-brown papules, typically lacking a follicular basis, and individually larger than sebaceous hyperplasia.
- Langerhans cell histiocytosis – Some variants of self-limited congenital histiocytosis may present with multiple red-brown papules.
Best Tests
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Management Pearls
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Therapy
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References
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Last Reviewed:08/30/2021
Last Updated:09/07/2021
Last Updated:09/07/2021