Self-healing cutaneous mucinosis is a rare form of localized mucinosis. This condition typically affects children between 1 and 15 years old, although rare cases in adults have also been described. It is characterized by an acute eruption of waxy papules and subcutaneous nodules on the head, extremities, and trunk in an otherwise healthy pediatric patient. There may be periorbital edema. A febrile prodrome may precede the cutaneous eruption. Mild systemic symptoms such as fever, myalgia, arthralgia, and weakness are common.

Self-healing cutaneous mucinosis is a self-limited condition. An infectious etiology has been postulated but not proven.