Spindle cell nevus in Adult
The natural history of a Reed nevus consists of an initial rapid growth phase, subsequent stabilization, and ultimately, involution. This transformation is accompanied by changes in clinical appearance and dermoscopic findings. The final involution may explain why the lesion is uncommon in older adults.
Because clinical, dermoscopic, and even histopathologic features of a Reed nevus may overlap with those observed in melanoma, accurate identification is important to avoid misdiagnosis and inappropriate treatment. Rare cases of malignant behavior for Spitz nevi and Reed nevi are generally thought to have actually been melanomas that were misdiagnosed.
A rare variant of a Reed nevus, termed hypopigmented Reed nevus, has all the typical characteristics of a Reed nevus but lacks the typical heavy melanin deposition.
I78.1 – Nevus, non-neoplastic
253038006 – Spindle cell nevus
Differential Diagnosis & Pitfalls