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Subepidermal calcified nodule
Other Resources UpToDate PubMed

Subepidermal calcified nodule

Contributors: Andrea C. Medina González MD, Susan Burgin MD
Other Resources UpToDate PubMed

Synopsis

Subepidermal calcified nodule (SCN), also known as Winer's nodular calcinosis or solitary congenital nodular calcification, is a rare form of calcinosis cutis that typically occurs in healthy infants and children. It is considered a form of idiopathic calcinosis cutis, not secondary to previously diseased skin as in dystrophic calcinosis cutis, nor due to metastatic deposits of calcium.

The typical clinical presentation is a solitary, verrucous or smooth papule or nodule on the head or neck in an otherwise healthy child. The majority of lesions are first noted by parents within the first 2 years of life, if not at birth. The largest case series found a 2:1 male predominance. Lesions are almost invariably painless.

The pathogenesis is unknown; however, it may result from underlying adnexal structure damage, previous trauma, or viral infection. SCN is frequently misdiagnosed as far more common entities such as verruca vulgaris, molluscum contagiosum, or epidermal inclusion cyst.

Codes

ICD10CM:
L98.8 – Other specified disorders of the skin and subcutaneous tissue

SNOMEDCT:
703086002 – Subepidermal calcified nodule

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Last Reviewed:11/11/2020
Last Updated:10/12/2022
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Subepidermal calcified nodule
A medical illustration showing key findings of Subepidermal calcified nodule : Ear, Neck
Clinical image of Subepidermal calcified nodule - imageId=1730361. Click to open in gallery.  caption: 'A white papule at the upper helix.'
A white papule at the upper helix.
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