Supernumerary nipple in Adult
These benign lesions occur in 1%-6% of the population worldwide, and 10% of cases are familial with an autosomal dominance inheritance pattern. Incidence has been reported as more common in males (7:1 male-to-female ratio). Most are single lesions below the regular nipple but may be multiple and bilateral.
SNs are often undetected at birth and are generally without symptoms. Some become more noticeable at adolescence, menstruation, or pregnancy when increased pigmentation, fluctuating swelling and tenderness, or lactation may be noted.
There are some studies that suggest an association between accessory breast tissue, including SNs, and renal anomalies. An increased incidence of ipsilateral Becker nevus has been noted. SNs are found in several multiple congenital anomaly syndromes, including Simpson-Golabi-Behmel (overgrowth, coarse face, embryonal tumors, and congenital cardiac, renal, and/or skeletal abnormalities), cleft lip or palate ectodermal dysplasia, and tricho-odonto-onychial dysplasia. Ectopic glandular breast tissue can develop any of the lesions of normal breast tissue, including malignancy.
Q83.3 – Accessory nipple
50956007 – Supernumerary nipple
Differential Diagnosis & Pitfalls