Trigeminal trophic syndrome
Most cases of trigeminal trophic syndrome are a complication of neurosurgical removal of the Gasserian ganglion, which is typically performed to treat intractable trigeminal neuralgia. Additional predisposing conditions include stroke, central nervous system (CNS) tumors (ie, astrocytoma or meningioma), infections (ie, herpes simplex virus [HSV], varicella-zoster virus [VZV], or leprosy), syringobulbia, vestibular schwannoma, postencephalitic parkinsonism, and vertebrobasilar insufficiency.
Trigeminal trophic syndrome can occur weeks or years after injury to the trigeminal nerve or sensory nuclei. It occurs more commonly in elderly patients and women.
G50.0 – Trigeminal neuralgia
403602005 – Trigeminal trophic syndrome
Differential Diagnosis & Pitfalls
- Chronic HSV
- Cutaneous tuberculosis (lupus vulgaris)
- Cutaneous leishmaniasis
- Mucocutaneous leishmaniasis
- Primary syphilis