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DDx Strength: Weak
rofecoxib, Rash or multiple lesions

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Exanthematous drug eruption

Exanthematous drug eruptionExanthematous drug eruption

Anaphylaxis

Anaphylaxis

Urticaria

UrticariaUrticaria

Angioedema

AngioedemaAngioedema

Drug-induced hepatotoxicity

Drug-induced hepatotoxicity

Pseudoporphyria

PseudoporphyriaPseudoporphyria

Ulcerative colitis

Ulcerative colitisUlcerative colitis

Vasculitis

VasculitisVasculitis

Stevens-Johnson syndrome

Stevens-Johnson syndromeStevens-Johnson syndrome

Aquagenic wrinkling of the palms

Aquagenic wrinkling of the palmsAquagenic wrinkling of the palms

Fixed drug eruption

Fixed drug eruptionFixed drug eruption

Psoriasis

PsoriasisPsoriasis

Erythema multiforme

Erythema multiformeErythema multiforme

Leukocytoclastic vasculitis

Leukocytoclastic vasculitisLeukocytoclastic vasculitis

Lichenoid drug eruption

Lichenoid drug eruptionLichenoid drug eruption

Acute febrile neutrophilic dermatosis

Acute febrile neutrophilic dermatosisAcute febrile neutrophilic dermatosis

Acute coronary syndrome

Acute coronary syndrome

Coronary artery disease

Coronary artery disease

Drug-induced abdominal pain

Drug-induced abdominal pain

Drug-induced diarrhea

Drug-induced diarrhea

Drug-induced dyspepsia

Drug-induced dyspepsia

Drug-induced nausea or vomiting

Drug-induced nausea or vomiting

Gynecomastia

GynecomastiaGynecomastia

Transient global amnesia

Transient global amnesia

Acute interstitial nephritis

Acute interstitial nephritis

Acute kidney injury

Acute kidney injury

Acute pancreatitis

Acute pancreatitis

Branch retinal vein occlusion

Branch retinal vein occlusion

Colitis

Colitis

Delirium

Delirium

Drug-induced constipation

Drug-induced constipation

Drug-induced dizziness

Drug-induced dizziness

Drug-induced esophagitis

Drug-induced esophagitis

Drug-induced fatigue

Drug-induced fatigue

Drug-induced headache

Drug-induced headache

Drug-induced hypertension

Drug-induced hypertension

Drug-induced oral ulcer

Drug-induced oral ulcerDrug-induced oral ulcer

Drug-induced somnolence

Drug-induced somnolence

Drug-induced stroke

Drug-induced stroke

Duodenal ulcer

Duodenal ulcer

Gastric ulcer

Gastric ulcer

Gastritis

Gastritis

GI bleeding

GI bleeding

Ocular drug reaction

Ocular drug reaction

Peptic ulcer disease

Peptic ulcer disease

Pulmonary edema

Pulmonary edema

Pulmonary embolism

Pulmonary embolismPulmonary embolism

Aseptic meningitis

Aseptic meningitis

Bowel perforation

Bowel perforationBowel perforation

Central retinal vein occlusion

Central retinal vein occlusionCentral retinal vein occlusion

Drug-induced heart failure

Drug-induced heart failure

Drug-induced hyperlipasemia

Drug-induced hyperlipasemia

Drug-induced paresthesia

Drug-induced paresthesia

Drug-induced psychosis

Drug-induced psychosis

Drug-induced weakness

Drug-induced weakness

Ischemic colitis

Ischemic colitis

Drug-induced hematemesis

Drug-induced hematemesis

Idiopathic intracranial hypertension

Idiopathic intracranial hypertensionIdiopathic intracranial hypertension

Spontaneous abortion

Spontaneous abortion

Sinus bradycardia

Sinus bradycardia