Contents

SynopsisCodesDifferential Diagnosis & PitfallsBest TestsDrug Reaction DataReferences
Emergency: requires immediate attention
Coronary artery aneurysm
Other Resources UpToDate PubMed
Emergency: requires immediate attention

Coronary artery aneurysm

Contributors: Christine Osborne MD, Ryan Hoefen MD, PhD
Other Resources UpToDate PubMed

Synopsis

Dilation of a coronary artery to >1.5 times the normal size. It may be a focal or diffuse process. Patients may be asymptomatic or may present with ischemic symptoms typical of coronary artery disease including chest pain, shortness of breath, and nausea. Underlying causes for development of coronary artery aneurysms include atherosclerosis, congenital aneurysms, and underlying inflammatory and connective tissue diseases such as Kawasaki disease, Takayasu arteritis, rheumatoid arthritis, Ehlers-Danlos syndrome, Marfan syndrome, and systemic lupus erythematosus. Iatrogenic causes such as percutaneous coronary intervention, trauma, and drug use may also lead to aneurysm formation. Aneurysm may occur in a saphenous vein coronary artery graft.

The right coronary artery is most commonly affected, followed by the left circumflex artery and the left anterior descending artery. Atherosclerosis is associated with 50% of all aneurysms, and congenital aneurysms account for 20%-30%, with the remainder due to underlying inflammatory and connective tissue diseases or iatrogenic causes.

Codes

ICD10CM:
I25.41 – Coronary artery aneurysm

SNOMEDCT:
50570003 – Aneurysm of coronary vessels

Differential Diagnosis & Pitfalls

Best Tests

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Drug Reaction Data

Below is a list of drugs with literature evidence indicating an adverse association with this diagnosis. The list is continually updated through ongoing research and new medication approvals. Click on Citations to sort by number of citations or click on Medication to sort the medications alphabetically.

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References

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Last Updated:08/28/2018
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Emergency: requires immediate attention
Coronary artery aneurysm
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A medical illustration showing key findings of Coronary artery aneurysm : Chest pain, HR increased
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