Nevus anemicus in Child
Alerts and Notices
SynopsisNevus anemicus is a cutaneous finding characterized by focal pallor of skin without textural irregularity due to congenital local hypersensitivity of cutaneous blood vessels to catecholamines. The vasoconstriction and subsequent pallor of the affected skin mimics hypopigmentation, but this usually congenital change has no associated pigmentary alteration. Nevus anemicus usually involves the trunk, but lesions on the face and extremities have been observed. It is usually first noticed at birth or in early childhood, but because it can often be subtle and is asymptomatic, it is frequently an isolated incidental finding.
Nevus anemicus may also occur in association with several syndromes, including neurofibromatosis (up to 4% of cases) and phakomatosis pigmentovascularis (PPV), a syndrome consisting of combinations of cutaneous and vascular findings that may include capillary malformations, dermal melanocytosis, and nevus spilus, caused by mutations in the GNAQ / GNA11 pathways. Nevus anemicus has also been seen in patients with Legius syndrome with confirmed SPRED1 mutation and Noonan syndrome with lentigines, with a confirmed PTPN11 mutation.
Q82.5 – Congenital non-neoplastic nevus
40929003 – Nevus anemicus
Differential Diagnosis & Pitfalls
- Nevus depigmentosus
- Tinea versicolor
- Ash leaf macules of tuberous sclerosis
- Hypopigmented macule of leprosy (anaesthetic)
- Hypopigmented mycosis fungoides
- Postinflammatory hypopigmentation
Patient Information for Nevus anemicus in Child
OverviewA nevus is commonly called a birthmark. A nevus anemicus is a patch of skin that is lighter than the surrounding skin. It is present at birth.
Nevi can be of various shapes and sizes. The border of the pale patch is irregular.
Who’s At RiskNevus anemicus is present at birth, but may be first noticed in early childhood. It is harmless and there is no increased risk of spread or malignancy.
Signs & Symptoms
- One or more pale patches of skin on the body's trunk, and sometimes on the neck, face, arms, and legs.
- Seen at birth or first observed in infants or young children.
- Unlike the surrounding normal skin, it does not turn red upon pressing or from heat and cold.
Self-Care GuidelinesNevus anemicus is a harmless condition that does not require treatment.
You can use cosmetics to cover the patch if you prefer.
When to Seek Medical CareYour child's pediatrician can check for pale skin patches and confirm the diagnosis is harmless. If you observe any other skin changes, consult your pediatrician to rule out other conditions.
TreatmentsNo treatments are needed for this benign condition.
Nevus anemicus in Child